PDRN is the K-Beauty Ingredient Blowing up on Socials (and Why We Use It at SSMD)

If you follow the latest Korean skincare trends, you’ve probably seen PDRN popping up everywhere. Short for polydeoxyribonucleotide, this powerhouse ingredient is derived from salmon DNA and is loved for its healing, anti-inflammatory, and skin-repairing properties.

While Hollywood has made headlines with injectable “salmon DNA facials,” PDRN isn’t just for in-clinic polynucleotide treatments. Thanks to K-Beauty innovation, it’s now found in serums, ampoules, moisturizers, and toners, making it possible to enjoy some of its benefits at home.

So what makes it special?
PDRN works by stimulating collagen production, boosting cell regeneration, and calming inflammation. It’s especially loved by those with dry, dull, or sensitive skin, and it’s gentle enough for post-procedure recovery.

That said, topical PDRN works more on the surface, while injectable or device-assisted delivery penetrates deeper for stronger results. That’s why at SSMD, we pair PDRN with microneedling or skin booster treatments, allowing this superstar ingredient to reach deeper layers of your skin where it can truly work its magic.

Benefits of PDRN:

1. Speeds up skin healing and recovery

2. Improves elasticity, tone, and texture

3. Strengthens the skin barrier

4. Provides a long-lasting “glass skin” glo

PDRN Skin Booster Treatment

Who should avoid it?

PDRN is generally well tolerated, but those with fish allergies or strict vegan lifestyles should opt for plant-based or lab-synthesized alternatives.

💉 Ready to try it?

Book a PDRN skin booster or microneedling session at SSMD and experience why this K-Beauty favorite is taking over the skincare world.